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doi: 10.1007/s11739-015-1361-y 36

If all who fail with A ( n = 90) try B and 20% succeed ( n = 18) while half of those who fail with B try A ( n = 40) and 10% succeed ( n = 4), the quit rates will be 28% ((10 + 18)/100) and 24% ((20 + 4)/100) in the A and B arms, respectively, masking the real 10% versus 20% treatment difference

And recent months have seen reports of serious respiratory illnesses and even deaths linked to vaping

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Experts are concerned this pattern could inhibit efforts by smokers trying to cut the habit and cause them to not explore more effective means of quitting (16)